A newborn baby has a prominent defect at the base of his spine through which his meninges and spinal cord protrude. A failure of which of the following processes is the most common cause of this type of defect (LQ)
|A||Development of primary vertebral ossification centers|
|B||Development of the pedicle|
|C||Development of the superior articular process|
|D||Fusion of the vertebral arches|
Vertebral arches mainly develop from posterior sclerotome (PS) and thus spina bifida is a defect of PS.
Spina bifida (Latin: "split spine") are birth defects caused by an incomplete closure (an opening) of one or more vertebral arches (lamina) of the spine, resulting in malformations of the spinal cord.
The spinal membranes and spinal cord may protrude through the absence of vertebral arches (called clefts). These malformations fall into two categories: spina bifida occulta & spina bifida cystica.
Depending on the extent of the types of tissue herniated; these defects can be classified as meningocele, meningoencephalocele, and as meningohydroencephalocoele.