1 out of 12
About Down's syndrome which of the following is/ are true: (AIIMS May 2012)
|A||Mongoloid slant for the eyes|
|B||Associated with jejunal atresia|
|D||Presence of simian crease|
Ans. A And D Mongoloid slant for the eyes, Presence of simian crease
a. Down's syndrome: Commonest chromosomal disorder (Trisomy 21)
b. MC cause is meiotic nondisjunction of ovum.
c. Associated with increased maternal age.
d. ↑ Risk of developing ALL and AML-M7.