All are about acarbose except: (LQ)
|A||It is α-glucosidase inhibitor|
|C||It retards conversion of overt hyperglycemia to typeII|
|D||ACT both on fasting and post prandial sugar|
a. Fibrinogen levels are reduced by acarbose (BG Katzung, Basic and Clinical Pharmacology; 10th Edition’ 2007, pp-700).
b. The drug not only reduces fibrinogen but also several other markers of inflammation are reduced.
c. Acarbose is a competitive inhibitor of intestinal alpha-glucosidase and inhibits the conversion of complex to simple carbohydrates.
d. Since the drug inhibits glucose absorption; it can also be used in type-1 diabetes and is used in postprandial hyperglycemia. Presence of lots of undigested carbohydrates leads to dyspepsia as a side effects.