All are derived from cholesterol except
|A||Chen deoxyCholic acid|
- Bile acid synthesis from cholesterol in liver: -
b. Testosterone: is synthesized in the interstitial tissue by Leydig cells, the immediate precursor of the gonadal steroids, is cholesterol. The rate limiting step, is delivery of cholesterol to the inner membrane of the mitochondria by the transport protein called - Steroidogenic acute regulatory protein (StAR)
- Cholecystokinin (CCK) → is polypeptide hormone, eg.
i. CCK 8 and CCK 12 (contain 8 and 12 amino acids) →secreted in duodenum and jejunum
ii. CCK 58 and CCK 8 (contain 58 and 8 amino acids) →are found in brain.
iii. Function →↑es secretion of pancreatic juice rich in enzymes