Diseases of PNS
All are true about mucormycosis, except: (LQ)
|C||Long term deferoxanine therepy|
|E||May lead to blindness|
Ref. (Current Otolaryngology 3rd/ed p 295)
k. Mucormycosis is caused by Rhizopus species, Rhizomucus and Absidia species.
• Intitially, the disease runs a subtle course with only fever and rhinorrhea. Latter on, it invades the orbit and intracranial cavity with rapid loss of vision, meningitis, cavernous sinus thrombosis and multiple cranial nerve palsies.
l. It has marked predilection for vascular invasion leading to widespread thrombosis, tissue necrosis, and gangrene.
m. Characteristic nasal finding is a dark necrotic turbinate surrounded by pale mucosa blackish discharge and crusts.
n. M/C site is middle turbinate followed by middle meatus and septum.
o. Investigation of choice is MRI, while biopsy is confirmatory.
Treatment: Includes amphotericin-B, heparin, hyperbaric oxygen, and debridement.