Liver & GIT
All of the following are true about fibrolamellar carcinoma of the liver except: (AIIMS NOV 09)
|A||More common in females|
|B||Better prognosis than HCC|
|C||AFP levels always greater than 1000|
|D||Occur in younger individuals|
The fibrolamellar variant of the HCC is associated with a more favorable prognosis. It arises in otherwise healthy young adults and may be discovered while still amenable to surgical resection. It is a distinctive variant of hepatocellular carcinoma
1. It is seen in young adults (20-40 yrs. of age)
2. It is more common in females.
3. Clinical Feature: Fever, Wight Loss, Enlarge liver, LFT.
4. It Metastasis to lungs & Lymph node.
5. It has better prognosis
6. It has no association with HBV or cirrhosis
7. It is grossly encapsulated mass (i.e. It is not a diffuse lesion).
8. AFP elevation is not seen in FibrolamellarCa
9. S. neurotensin level.
10. Treatment surgery