All the following are connective tissue manifestations of hemophilia except
|C||Large soft tissue hematoma which degerates into a malignant tumor|
Large soft tissue hematoma which degerates into
a malignant tumor
a. Recurrent intra articular bleeding may lead to chronic synovitis and progressive articular destruction. Bleeding into the muscles is less common but equally harmful, increased tension leads to muscle necrosis reactive fibrosis and joints contracture. Sometimes nerves are compressed causing a neuropraxia, temporary weakness may further contribute to development of joint deformity.
b. Cysts and pseudotumors are rare phenomenon. A large hematoma may become encapsulated before it is absorbed and may then draw in more fluid by osmosis to produce a slowly expanding cyst, malignant transformation is rare.