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Pediatric Nasopharyngeal Tumors

  1. Chordoma:
    Features: Slow-growing tumor of low malignancy
    1. Occurs along the craniocervical axis (clivus, nasopharynx, C1 & C2)
    2. Erodes bone extensively
    3. Not very sensitive to radiotherapy
  2. Craniopharyngioma:
    1. Derived from the remnants of Rathke’s pouch
    2. Is devoid of definite capsule
    3. Tumor proper is soft with multiple septae
    4. Calcification may be present
    5. Treatment: Surgical removal
  3. Furstenberg Sign:
    Enlargement of the nasopharyngeal cyst with crying or jugular vein compression. Occurs in those communicating intracranially.

MCQ. Jugular foramen syndrome is paralysis of CN IX, X and XI. It is seen in carcinoma nasopharynx,
glomus jugu­lare, large acoustic neuroma or thrombophlebitis of jugular bulb.
MCQ. In any case of unilateral otitis media with effusion in an adult, rule out nasopharyngeal pathology
especially carcinoma nasopharynx.
MCQ. Trotter’s (or Sinus of Morgagni) syndrome or triad is seen in nasopharyngeal carcinoma which spreads later­ally to involve the sinus of Morgagni involving in mandibular nerve. It is characterised by:

  1. Conductive hearing loss (due to eustachian tube obstruction).
  2. Ipsilateral immobility of soft palate.
  3. Neuralgic pain in the distribution ofV3.



Extra Edge

Carcinoma of nasopharynx is caused, among other factors, by Epstein-Barr virus. Most common site of origin is fossa of Rosenmuller (pharyngeal recess). Most common histological variety is squamous cell carcinoma, and radiotherapy is the treatment of choice.

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