Gram Negative Coccobacilli
Brucella is pathogenic for humans and animals, which one of the following statements best characterizes this organism?
|A||It cause spontaneous abortion and has tropism for placental tissue due to the presence of erythritol in allantoic and amniotic fluid|
|B||It has a capsule of polyglutamic acid, which is toxic when injected into rabbits|
|C||It has 82 polysaccharide capsular types; capsule is antiphagocytic; type 3 capsule (b-d-glucuronic acid polymer) most commonly seen in injected adults|
|D||It secretes two toxins, A and B, in the large bowel during antibiotic therapy|
a. There are no known toxins, hemolysins, or cell-wall constituents known to play a role in the pathogenesis of disease by Brucella. Rather, the ability of the organisms to survive within the host phagocyte and to inhibit neutrophil degranulation is a major disease-causing factor.
b. In infectious abortion of cattle caused by Brucella, the tropism for placenta and the chorion is a function of the presence of erythritol in allantoic and amniotic fluid.
Extra Edge: OIE: Office International des Epizootis.