Epileptogenic anesthetic agent?
(Ref. Complications in anesthesiology by Emilio B. Lobato - Page 315)
a. Like enflurane, even Sevoflurane is moreorless supposed to be Epileptogenic anesthetic agent.
b. Sevoflurane has similar effects as isoflurane on ICP and CPP in humans with intracranial pathology. Sevoflurane may have epileptogenic activity similar to enflurane.
c. The addition of NO to sevoflurane precipitiously increases CBF and impairs autoregulation.