Gram Negative Spiral
H.Pyloric is Carcinogenic due to all except:
|C||Elaboration of interleukin|
|D||Causes RNA splicing|
Causes RNA splicing Reference: Ananthanarayanan 7th Edition Page 408
a. The disease causing strains of Helicobacter pylori contain a “pathogenicity island” containing the CagA (cytotoxin associated gene A) and a secretory system which injects the CagA protein into the host cells.
b. Another gene associated with virulence is Vac A, which encodes a vacuolating toxin that causes apoptosis Infection with H. pylori is associated with gastric adenocarcinomas of the intestinal through a sequence that involves chronic gastritis, multifocal atrophy with lower gastric acid secretion, intestinal metaplasia, dysplasia and carcinoma.