In MI, thrombolytics can be given if patient comes within (AIIMS May 2012)
12hrs (Ref: Hari-18th ed., pg-2027)
1. In acute MI, myocardium can be salvaged only before it has been irreversibly injured, the timing of reperfusion therapy, by fibrinolysis or a catheter-based approach, is of extreme importance in achieving maximum benefit.
2. While the upper time limit depends on specific factors in individual patients, it is clear that every minute counts and that patients treated within 1–3 h of the onset of symptoms generally benefit most.
3. Although reduction of the mortality rate is more modest, the therapy remains of benefit for many patients seen 3–6 h after the onset of infarction, and some benefit appears to be possible up to 12 h, especially if chest discomfort is still present and ST segments remain elevated.