In Myasthenia Gravis, correct statement regarding thymectomy is : (AIPG 2010)
|A||Should be done in all cases of generalized myasthenia between the age 20-55.|
|B||Should be done in cases with ocular involvement only|
|C||Not required if controlled by medical management|
|D||Should be done only in cases that are associated with thymoma|
Should be done in all cases
Thymectomy is therefore recommended as a form of treatment for MG.
1). Patients with thymomas
a. Thymectomy should be carried out in all patients who have thymomas
b. Thymectomy in thymonas is necessary because of the possibility of local tumor spread although most thymomas are benign.
2). Patients without thymomas
Thymectomy should be carried out in all patients with generalized MG who are between the ages of puberty and at least 55 years
3). Thymectomy not recommended for:
a. Children (<puberty)
b. Elderly >55 years
c. Localized M. G. with weakness limited to extra ocular muscles
d. Patients with MUSK antibody positive Myasthenia gravis.
1). Thymoma is a tumor originating from the thymus. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant and probably not neoplastic.
2). Thymoma usually is benign, and frequently encapsulated; when occasionally malignant, then it is invasive: distant metastasis are rare.
3). It is not associated with SIADH.