Increased nuchal translucency at 14 weeks of gestation is seen in: (DNB, Nov. 2008)
|D|| Klinefelter's syndrome|
a. Increased fetal nuchal thickness is a strong marker for chromosomal anomalies in the first trimester.
b. Increased fetal nuchal translucency i.e. > 3 mm on transvaginal ultrasound is suggestive of
i. Trisomy 21- Down's syndrome
ii. Trisomy 18 – Edward syndrome
iii. Trisomy 13 - Patau syndrome
iv. Turner's syndrome
c. Most common chromosomal anomaly is Down's syndrome and hence the answer.