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4 out of 4

Loss of social inhibition occurs when the site of disease is? (PNQ)

A S2-4
B T10 – T12

C T3-T4
D Frontal cortex

Ans. D

Frontal cortex

Types of urinary bladder disturbance

I. Autonomous / Hypotonic bladder – Q

a. Lesion at S2, S3, S4

b. Large capacity bladder.

c. Distention with overflow

II. Complete spastic / automatic / Hypertonic bladder Q

a. Lesion in the spinal segment above S2, S3, S4

b. Small capacity bladder

c. Frequent voiding at interval (Bladder start behaving like bladder of a new born baby)

III. Cortical / Uninhibited Bladder

Frontal - Inappropriate micturition, loss of social inhibition control.

Recent Advances:

1. Overactive bladder (OAB) is defined by symptoms of urgency, with or without urinary incontinence, usually with frequency and nocturia.

2. This is a common condition in people older than 45 years, and symptoms are similar to those of BHP in males and incontinence in females.

3. Anticholinergic drugs, are used in the treatment of this condition.

4. Recent drugs, oxybutynin and tolterodine & Trospium are efficacious in treating OAB.