Measles vaccine given to a contact of measles case exerts protective effect within:
Some important facts about measles:
1. Incubation period is commonly 10 days from exposure to onset of fever, and 14 days to appearance of rash. When measles infection is artificially induced by-passing the respiratory tract (as with injection of live measles vaccine), the incubation period is somewhat shortened, averaging 7 days.
2. The vaccine has convincingly demonstrated to provide immunity to even severely malnourished children. Immunity develops 11 to 12 days after vaccination and appears to be of long duration, probably for life. One dose of the vaccine appears to give 95 per cent protection.
3. Susceptible contacts over the age of 9-12 months may be protected against measles with measles vaccine, provided that this is given within 3 days of exposure. This is because the incubation period of measles induced by the vaccine is about 7 days, compared with 10 days for the naturally acquired measles.
- All are tissue culture vaccine; HDC -Edmonston Zagreb strain vaccine may protect children from 4-6 months of age.
- Diluent to be used is distilled water and reconstituted vaccine should be kept on ice and used within one hour
- Measles vaccine has recently been adopted for aerosol administration.
- Measles illness is a mild fever and rash developing 5-10 days after immunization
- Immunity develops 11-12 days after vaccination
- Pregnancy is a contraindication for vaccination other C/I are acute illness, deficient CMI
- Toxic shock syndrome result as adverse effect of vaccine because of contamination
- Live measles vaccine should be given 8-12 weeks after immunoglobulin.