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Caffey’s Disease

  1. Infantile cortical hyperostosis (Caffey’s Disease)
    1. is a self limiting disorder characterized by soft tissue swelling rapid subperiosteal new bone formation, cortical thickening of underlying bones, fever and irritability.
    2. Classically, the onset of disease occurs before 5th month of life with resolution by 3 years of age.
    3. In sporadic cases, mandible is the most common site of involvement presenting as jaw tumor or swelling i.e. is firm, tender with out heat or redness.
    4. Presence of raised ESR & alkaline phosphatase & anemia mimic infection
    5. Tibia> ulna are most frequently involved in familial form.

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