Osteoblastic nature seen with
a. In general, mets have little or no soft tissue mass associated with them.
b. Usually no periosteal reaction
c. May appear as moth-eaten, permeative or geographic lesions
i. Indistinct zones of transition
ii. No sclerotic margins
iii. May be expansile
iv. Soap-bubbly (septateD.
v. May be sharply circumscribed or have indistinct borders
Metastases that are typically purely lytic
Metastases that are usually mixed lytic and sclerotic
Metastases that are usually purely blastic
iii. Bronchial carcinoid
No matter what the primary, skull metastases are usually lytic in appearance