Production of fructose in seminal fluid is by following steps
|A||glucose — 6 — phosphate → fructose — 6 phosphate →fructose|
|B||Glucose —6— phosphate → sorbitol phosphate <<fructose phosphate → fructose|
|C||Glucose — 6 — phosphate → glucose →sorbitol <<fructose|
|D||Glucose — 6— phosphate << fructose — 1 — phosphate << fructose|
Fructose is abundantly present in seminal fluid, and is principle source of energy of spermatozoa. It is formed from glucose in the seminal vesicle in the following manner.
a. Aldose reductase is absent in liver, but found in many tissues like lens and retina of the eye, kidney,
placenta, Schwann cells, RBC, and seminal vesicle.
b. Sorbitol dehydrogenase (deHase) is present in liver, seminal vesicle, spleen, and ovaries.