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Xanthogranulomatous pyelonephritis

  1. Is a rare type of renal infection characterized by granulomatous inflammation with giant cells and foamy histiocytes.
  2. It may present clinically as a renal mass or an acute or chronic infection.
  3. Renal calculi, obstruction, and infection with Proteus or E. coli contribute to the development of this lesion, which usually requires total or partial nephrectomy.

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