Gram Negative Cocci
Several days after an unprotected sexual encounter, a healthy 21-yrs-old male develops pain and pus on urination. A Gram stain reveals gram-negative diplococci. Which of the following structures is most responsible for adherence of the offending microbe to the urethral mucosa?
|D||The F pili|
a. Typical Neisseria are gram-negative diplococci. N.
b. gonorrhoeae contain pili, hairlike appendages that may be several micrometers long. They enhance attachment of the organism to mucous membranes, helping to make the organism more resistant to phagocytosis by white blood cells.
c. Gonococci isolated from clinical specimens produce small colonies containing piliated bacteria. Capsules appear to be less important in gonococcal infection than N. meningitidis infections.
d. Flagella, peptidoglycan, LPS, and F pill do not significantly relate to patho genesis, other than that LPS (endotoxin) release may become significant later in infection.