The best accounted function of MIP-26 in lens (AIPG2009)
|B||Maintains lens transparency|
1. Proteins of the lens plasma membranes constitute to no more than 1% of the lens wet weight, they are critically important for the lens function including transparency.
2. MI26 is a lens fiber-specific integral membrane protein, which mediates the passage of small molecules through the membranes.
3. It does not form an intercellular channel as do the connexons in gap junctions but may form channels to the extracellular space, possibly providing indirect connections or helping to minimize the extracellular space and enhance less transparency.