35 out of 75
The molecule, which is the initiator of cataract formation in the eye lens and whose 1-phosphate derivative is responsible for liver failure, is: (LQ)
Ans. D Galactitol
1. In classic galactosemia, galactose-1-phosphate-uridyl transferase (GALT) Q deficiency results in tissue accumulation of galactose-1-phosphate and galactose.Q
2. Cataracts develop secondary to galactitol accumulation in the lens.