Vitamins, Harmones and Hemoglobin
True regarding conversion of deoxyhemoglobin to oxyhemoglobin is:
|A||Binding of O2 causes release of H+|
|B||One mole of deoxyhemoglobin binds two moles of 2,3 DPG.|
|C||pH of blood has no affect on the binding of O2|
|D||Binding of O2 causes increased binding of 2,3 DPG.|
Binding of O2 to deoxyhemoglobin in lungs causes release of proton (H+). This is responsible for Bohr effect.
One mole of deoxyhemoglobin binds one mole of 2,3 DPG.
2,3- DPG binds to deoxygenated (T) form of Hb & binding of O2 to Hb decreases the binding of 2,3-DPG.
2,3-DPG decreases the affinity of Hb molecule for O2 thus increase in DPG conc, shifts O2- Hb dissociation curve to right.