2 out of 7
Two siblings with Osteogenesis imperfecta, but their parents are normal. Mechanism of inheritance is explained by: (AIPG 2012)
|C||Germ line mosaicism|
Ans. C Germ line mosaicism
In some autosomal dominant disorders, exemplified by osteogenesis imperfecta, phenotypically normal parents have more than one affected child.