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Sarcoid uveitis accounts for 2 percent cases of uveitis and may occur as:

  1. Chronic bilateral granulomatous iridocyclitis occurs in older patients with chronic lung disease.
  2. Uveoparotid fever (Hereditary syndrome):Bilateral granulomatous panuveitis, painful enlargement of parotid glands, cranial nerve palsies, skin rashes, fever and malaise.
  1. Ocular Features-
    1. Sarcoid plaques, sarcoid granulomata over the eyelids
    2. Anterior segment lesion - Involvement of conjunctiva, episclera, sclera
    3. Dry eye – due to involvement of lacrimal gland
    4. Anterior uveitis –     
      • Acute or chronic granulomatous iridocyclitis
  2. Diffuse vitritis - Snow ball opacities in vitreous*
  3. Fundus changes
    1. Periphlebitis - Advanced stage of vascular sheathing lead to candle – wax drippings
    2. Retinal granulomata and Pre-retinal nodules – Lander’s sign*
    3. Optic nerve lesions
      1. Disc granuloma
      2. Papilloedema
      3. Neovascularization
      4. Optic atrophy

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