Diseases & National Health Programme
Which is the most efficacious vaccine?
Measles vaccine has a protective efficacy of 95% with single dose while DPT vaccine has an efficacy of 70%. As far as polio vaccine is concerned the efficacy is quite variable for the three viral strains ranging from 65 – 90%. Moreover enteroviruse which are normally present in the intestine also antagonize the protective antibody response. However, Adsorbed tetanus toxoid (vaccine efficiency of 100%)has very high protective efficacy with vaccine failures recorded in less than 1% cases.