Which of the following is most important in a diagnosis of Mixed Connective tissue disorder?
|B||Anti ds DNA ab|
|C||Anti Sm ab|
|D||U1 RNP antibodies|
Mixed Connective Tissue Disorder (MCTD)
Definition- It is an overlap syndrome characterized by a combination of clinical features similar to those of SLE, scleroderma & polymyositis.
Diagnosis is confirmed by detection of unusually high titers of circulating U1 RNP antibodies (FAQ)
i. Salicylates and other NSAID