General Virology and DNA Viruses
Which of the following is not true about Parvovirus?
|A||It is a DNA virus.|
|B||Causes anaemia by depression of bone marrow erythrocytic progenitor cells.|
|C||Spreads by respiratory route|
|D||Trans–placental spread occurs in < 10% of cases.|
a. Maternal infection with B19 virus may pose a serious risk to the fetus, resulting in hydrops fetalis and fetal death due to severe anemia.
b. The overall risk of human parvovirus infection during pregnancy is low; fetal loss occurs in less than 10% of primary maternal infections.
c. Fetal death occurs most commonly before the 20th week of pregnancy.
d. Although there is frequent intrauterine transmission of human parvovirus (with estimates of vertical transmission rates of 30% or higher), there is no evidence that B19 infection causes physical abnormalities.