Which of the following is the most likely inheritance pattern in the pedigree given below - (AIPG 2010)
X linked dominant
o It is an X linked dominant patten of inheritance.
o The features which suggests the X-linked dominant pattern of inheritance are-
• A single abnormal X chromosome is sufficient to express the disease.
• All of the female offsprings of a diseased male XY will receive the abnormal X chromosome and express the disease, whereas none of the male offspring to the diseased father will have the disease (as sons don't receive X chromosome from their father).
• A diseased mother can transmit the abnormal X chromosome to both daughter and sons equally.