Which of the following is a serious adverse effect seen with bisphosphonates? (LQ)
|A||Acute renal failure|
a. Actually the answer to this question should be none of these.
b. Bisphosphonates cause esophageal toxicity and should] avoided in peptic ulcer. However, they themselves do not cause peptic ulcer. Further, esophagitis is not serious adverse effect.
c. The serious adverse effect noted with most of bisphosphonates is osteonecrosis of jaw bone.
d. Zolendronate can cause serious side-effects as nephrotoxicity and renal failure.
e. Thus, probably the examiner wants to know about this adverse effect of zolendronate and mistakenly has given Bisphosphonates in the question rather than given zolendronate per se.