Which of the following statements concerning immunoglobulins is wrong: (AIIMS Nov 09)
|A||IgM does not cross placenta|
|B||IgE increased in parasitic infection|
|C||IgM increased in primary response|
|D||Fetal infection can be diagnosed by detection of IgG|
a. Only IgG can cross placenta, other classes cannot cross placenta, it is the predominant antibody present in secondary immune response.
b. IgM antibody is raised in primary immune response. IgE antibody is raised in parasitic infection and type I hypersensitivity reaction.
c. Fetal infection can be diagnosed by detection of specific IgM antibodies as IgG antibodies can be present in the baby due placental transfer from the mother.