Which of the following statements about hydralazine is not true (DNB June 2012)
|A||It causes direct relaxation of the blood vessels|
|B||It causes dilatation of both arteries and veins|
|C||Postural hypotension is not a common problem|
|D||It increases plasma renin activity|
Hydralazine is a predominantly arteriolar dilator that relaxes blood vessels by releasing NO and opening K+ channels. There is compensatory increase in plasma renin activity with all vasodilators. Postural hypotension is predominantly caused by dilatation of veins and is not a significant feature of hydralazine.